Name :
CD46 (Human) Recombinant Protein
Biological Activity :
Human CD46 (P15529, 35 a.a. – 313 a.a.) partial-length recombinant protein with His tag at C-Terminus expressed in Baculovirus.
Tag :
Protein Accession No. :
P15529
Protein Accession No.URL :
https://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4179
Amino Acid Sequence :
ADLCEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVSNYPGYPKPEEGILDSLDHHHHHH
Molecular Weight :
32.5
Storage and Stability :
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
Host :
Nicotiana benthamiana
Interspecies Antigen Sequence :
Preparation Method :
Baculovirus expression system
Purification :
Quality Control Testing :
Storage Buffer :
PBS (pH7.4) and 10% glycerol.
Applications :
SDS-PAGE，
Gene Name :
CD46
Gene Alias :
MCP, MGC26544, MIC10, TLX, TRA2.10
Gene Description :
CD46 molecule, complement regulatory protein
Gene Summary :
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene. [provided by RefSeq
Other Designations :
CD46 antigen, complement regulatory protein|OTTHUMP00000034577|OTTHUMP00000034622|OTTHUMP00000034623|OTTHUMP00000034624|OTTHUMP00000034625|OTTHUMP00000034626|OTTHUMP00000034706|antigen identified by monoclonal antibody TRA-2-10|complement membrane cofacto
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Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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