Cynomolgus/Rhesus macaque CD47 Protein 3223

Additional Information:
accession F7A802|express systemHEK293|product tagC-His|purity> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC|backgroundCD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRP).CD-47 acts as a don’t eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.|molecular weightThe protein has a predicted MW of 15 kDa. Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.|available size100 g, 500 g|endotoxinLess than 1EU per g by the LAL method.|Cynomolgus/Rhesus macaque CD47 Protein 3223proteinSize and concentration100, 500g and lyophilizedFormLyophilizedStorage InstructionsValid for 12 months from date of receipt when stored at -80C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.Storage bufferShipped at ambient temperature.Purity> 95% as determined by Tris-Bis PAGEtarget relevanceCD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRP).CD-47 acts as a don’t eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers.Protein namesLeukocyte surface antigen CD47 (Integrin-associated protein)Gene namesCD47,CD47Mass9544DaSubellular locationCell membrane ; Multi-pass membrane protein. Membrane ; Multi-pass membrane protein .Target Relevance information above includes information from UniProt accession: F7A802The UniProt Consortium|