Product Name :
Rabbit anti-Phospho-Stat5(Tyr694/699) Polyclonal Antibody
Synonym :
Host :
Rabbit
Species Reactivity:
Human, Mouse, Rat
Specificity :
Predicted Reactivity:
Applications :
WB: 1:500-1:2000, IHC: 1:100-1:300, ELISA: 1:20000. Not yet Ted in other applications.
Immunogen:
Peptide-KLH
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Store at -20℃ for one year.
Research areas :
Background :
signal transducer and activator of transcription 5A(STAT5A) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been
UniProt :
P42229/P51692
Additional information:
Product Details FAQ Citations(0) Video Pictures Documents |Overview |Host Rabbit |Species Reactivity Human, Mouse, Rat |Applications WB: 1:500-1:2000, IHC: 1:100-1:300, ELISA: 1:20000. Not yet Ted in other applications. |Immunogen Peptide-KLH |Properties |Form Liquid |Clonality Polyclonal Antibody |Isotype Rabbit IgG |Storage Temp. Store at -20℃ for one year. |Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |Target |Background signal transducer and activator of transcription 5A(STAT5A) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been |UniProt P42229/P51692 |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-Phospho-Stat5(Tyr694/699) Polyclonal Antibody
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
2068-78-2 supplier 64221-86-9 In stock PMID:25905331 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
